Osserman also mentions that the use of quinidinea relative of quinineis contraindicated in myasthenia, and instead advises the use of procainamide hydrochloride or digitalis. Dec 1 20Drugs implicated as potentially harmful in myasthenia gravis patients based on either anecdotal case reports or in-vitro microelectrode studies Beta blockers Propanolol. Cautionary Drugs - Myasthenia Gravis Checkpoint inhibitors: Immunotherapy for cancer is an exciting treatment advance for many types of cancers. Procainamide: Indications, Side Effects, Warnings - m Mar 0 20Myasthenia gravis that has gotten worse has happened during treatment with procainamide.
Amiloride: (Moderate) Procainamide can decrease blood pressure and should be used cautiously in patients receiving antihypertensive agents. Check with your physician if you have any of the following. You will need to talk about the benefits and risks of using procainamide while you are pregnant. Procainamide - Side Effects, Dosage, Interactions - Drugs Procainamide is a prescription medicine thataposs used to treat abnormal heart rhythms, including atrial fibrillation and atrial flutter. However, one newly recognized rare side effect of some of these treatments is myasthenia gravis (MG).
Patients with myasthenia gravis may show worsening of symptoms from PA due to its procaine-like effect on diminishing acetylcholine release at skeletal muscle motor nerve endings, so that PA administration may be hazardous without optimal adjustment of anticholinesterase medications and other precautions).
Tell your doctor if you are pregnant or plan on getting pregnant. Drugs to Avoid in Myasthenic Crisis - Neurology - Michigan. Procainamide also has anticholinergic properties, albeit somewhat less than disopyramide. MG is recognized as a rare complication of immune checkpoint inhibitors (ICIs) for cancer (immunotherapy). Sep 0 19In 194 Weisman noted that the use of quinidine sulfate to treat a cardiac arrhythmia in a patient with myasthenia resulted in an increase of her weakness.
If you are or older, use procainamide with care. These antiarrhythmics should be used cautiously in patients with myasthenia gravis.
Procainamide - FDA prescribing information, side effects
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