Esketamine clinical trials 2019

Ketamine Advocacy Network - Find a Clinical Trial May 2 20A phase clinical trial testing esketamine nasal spray in the treatment of severe depression found the spray mostly safe and effective. Sanacora has been involved in several of the esketamine trials and has also served as a consultant to Janssen. Controlled clinical trials that studied the safety and efficacy of this drug, along with careful review through the FDAs. Participants will self-administer esketamine nasal spray, under the supervision of the healthcare professional at the site of care.

Jul 1 20The purpose of this study is to assess the efficacy of intranasal esketamine plus an oral antidepressant compared with an oral antidepressant (active comparator) plus intranasal placebo in delaying relapse of depressive symptoms in participants with treatment-resistant depression (TRD) who are in stable remission after an induction and.

Esketamine C13H16ClNO - PubChem

Sep 0 20This double-blin randomized clinical trial (A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-Resistant Depression SUSTAIN -1) used a randomized withdrawal design and was conducted from October 201 to February 1 2018. A starting dose of milligram (mg) will be administered intranasally into each nostril on Day with subsequent doses of mg or mg administered during Weeks 1-(treatment sessions per week). On March 201 the nasal spray drug, esketamine, also known as Spravato (by Janssen Pharmaceuticals was approved by the FDA for treatment-resistant major depression. Esketamine is the s-enantiomer of.Ketamine is a mixture of two enantiomers (mirror image).

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A Study of Intranasal Esketamine Plus an Oral

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