Thursday, March 15, 2018

Atypia of undetermined significance

Atypia of undetermined significance

Vol Issue p.7-American Thyroid Association Atypia of undetermined significance (AUS) and follicular lesion of undetermined significance (FLUS ) are a major part of the indeterminate category. Atypical squamous cells of undetermined significance is the most common abnormal finding in a Pap test. The AUS category will potentially reduce the number of false-negative diagnoses in the Non-Neoplastic category as well as reducing the number of false positive.


Jul 2 20Atypia of Undetermined Significance (AUS) Follicular Lesion of Undetermined Significance (FLUS ) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. (PDF) Atypia of Undetermined Significance In the Milan System, salivary gland fine-needle aspiration (FNA) samples that are indefinite for a neoplastic condition are classified as Atypia of Undetermined Significance (AUS). An important aspect of this system is that each diagnostic category is associated with relative risk of malignancy).

Malignancy rate in thyroid nodules categorized as atypia

Vol Issue p.7-American Thyroid Association

With the Bethesda system, the category of atypia of undetermined significance or follicular lesion of undetermined significance (Bethesda III) was introduced to capture cases in which the features are not readily classified as benign, suspicious, or malignant. It may also be a sign of a benign (not cancer) growth, such as a cyst or polyp or, in menopausal women, of low hormone levels. Listing a study does not mean it has been evaluated by the U.S. Atypia of undetermined significance (AUS) or follicular lesion of undetermined significance (FLUS ) of Bethesda system for reporting thyroid cytopathology has emerged as most controversial category due to its heterogeneity and inconsistent usage.


Feb 2 20The Bethesda six-category diagnostic scheme consisted of benign, atypia of undetermined significance (AUS suspicious for follicular neoplasm, suspicious for malignancy, malignant, and unsatisfactory. Most of these patients undergo a repeat biopsy and a large number of patients undergo surgical removal of their thyroid nodules for a definitive diagnosis. It may be a sign of infection with certain types of human papillomavirus (HPV). participants were asked to use vitamin E supplements and participants received a placebo.

What are Atypical Squamous Cells of Undetermined Significance?

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(PDF) Atypia of Undetermined Significance

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